Secondary plasma cell leukemia

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Secondary plasma cell leukemia.

Plasma cell leukemia (PCL) is a rare disease and is the least common variant of multiple myeloma accounting for 2-3% of all plasma cell dyscrasias. We report a patient who was diagnosed with multiple myeloma, 12 months earlier; he was treated with VBCMP, VCMP regime, and after 12 months he presented of high grade fever, weakness, palpitations, loss of appetite, bone pains, dyspnea. Initial eval...

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Survival of patients with multiple myeloma has improved substantially because of availability of new therapies including autotransplants, immunomodulating drugs and proteasome-inhibitors. Second primary cancers have emerged as an important determinant of morbidity and mortality among cancer survivors. Even though there is an increased risk of new cancers of the lymphoreticular and haematopoetic...

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Multiple myeloma and secondary plasma cell leukemia.

Plasma cell leukemia is very rare condition characterized by malignant proliferation of plasma cells in blood and bone marrow, which is aggressive and has a short survival even with conventional treatment. This ominous entity may be primary, or develops secondarily during the course of multiple myeloma. A 53-year-old Brazilian woman with multiple myeloma is described with bone marrow evaluation...

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Leukemia Cutis Associated with Secondary Plasma Cell Leukemia

Plasma cell leukemia is an uncommon, aggressive variant of leukemia that may occur de novo or in association with multiple myeloma. Leukemia cutis is the cutaneous manifestation of leukemia, and indicates an infiltration of the skin by malignant leukocytes or their precursors. Plasma cell leukemia cutis is a rare clinical presentation of leukemia. We present a man who developed plasma cell leuk...

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Plasma cell leukemia

Paciente do gênero feminino, 74 anos, procurou o hospital com quadro de insuficiência renal e lesões líticas em coluna vertebral, sendo feito diagnóstico de mieloma múltiplo IgG kappa. Na ocasião, observaram-se monossomia do cromossomo 13 e rearranjo do IgH no FISH. A paciente foi submetida a cinco ciclos de VMP (bortezomibe, melfalan e prednisona) com resposta com pleta; foi iniciada a manuten...

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ژورنال

عنوان ژورنال: Revista de Medicina de Laboratorio

سال: 2021

ISSN: 2660-7638,2660-7484

DOI: 10.20960/revmedlab.00073